Research Papers

In this page you will find several research papers that have used our equipment over the course of the years.

Ceballos, I. F., Steinberg, E., Ems, J., Nuñez Silveira, J. M., Madorno, M., Bisso, I. C., ... & Cornejo, R. (2024). Efectos fisiológicos del alto flujo de oxígeno medido por tomografía de impedancia eléctrica en trasplante unipulmonar. Medicina (Buenos Aires), 84(1), 148-152.

Tong, Y., Udupa, J. K., McDonough, J., Wu, C., Xie, L., Hao, Y., ... & Cahill, P. (2024). Virtual Growing Child (VGC): A general normative comparative system via quantitative dynamic MRI for quantifying pediatric regional respiratory anomalies with application in thoracic insufficiency syndrome (TIS). bioRxiv, 2024-04.

Tong, Y., Udupa, J. K., McDonough, J. M., Wu, C., Akhtar, Y., Xie, L., ... & Cahill, P. J. (2024, April). A normative database of free-breathing thoracic 4D dynamic MRI images and associated regional respiratory parameters of healthy children. In Medical Imaging 2024: Imaging Informatics for Healthcare, Research, and Applications (Vol. 12931, pp. 235-240). SPIE.

Dianti, J., Morris, I. S., Bassi, T. G., Fan, E., Slutsky, A. S., Brochard, L. J., ... & Goligher, E. C. (2024). Sedation-Ventilation Interaction in Acute Hypoxemic Respiratory Failure: Secondary Analysis of the LANDMARK Trial. CHEST Critical Care, 100067.

Tong, Y., Udupa, J. K., McDonough, J. M., Wu, C., Xie, L., Alnoury, M., ... & Cahill, P. J. (2024, March). Analysis of the dynamic architecture of the thorax and abdomen in pediatric patients with thoracic insufficiency syndrome (TIS) via dynamic MRI. In Medical Imaging 2024: Image-Guided Procedures, Robotic Interventions, and Modeling (Vol. 12928, pp. 291-295). SPIE.

Vieira, F. N., Masy, V., LaRue, R. J., Laengert, S. E., De Lannoy, C. F., Rodrigues, A., ... & Brochard, L. J. (2024). An individual barrier enclosure actively removing aerosols for airborne isolation: a vacuum tent. Respiratory Care, 69(4), 395-406.

Riva, D. A., Evangelista, C. A., Puleston, P. F., Corsiglia, L., & Dargains, N. (2024). Nonlinear identification algorithm for online and offline study of pulmonary mechanical ventilation. arXiv preprint arXiv:2402.18709.

Bello, G., Giammatteo, V., Bisanti, A., Delle Cese, L., Rosà, T., Menga, L. S., ... & Grieco, D. L. (2024). High vs. Low PEEP in ARDS Patients Exhibiting Intense Inspiratory Effort During Assisted Ventilation: A Randomized Crossover Trial. Chest.

Dianti, J. (2023). Monitoring and Controlling Respiratory Effort in Acute Hypoxemic Respiratory Failure (Doctoral dissertation, University of Toronto (Canada)).

Arellano, D. H., Brito, R., Morais, C. C., Ruiz-Rudolph, P., Gajardo, A. I., Guiñez, D. V., ... & Cornejo, R. A. (2023). Pendelluft in hypoxemic patients resuming spontaneous breathing: proportional modes versus pressure support ventilation. Annals of Intensive Care, 13(1), 1-11.

Parfait, M., Rohrs, E., Joussellin, V., Mayaux, J., Decavèle, M., Reynolds, S., ... & Dres, M. (2023). An Initial Investigation of Diaphragm Neurostimulation in Patients with Acute Respiratory Distress Syndrome. Anesthesiology, 10-1097.

Acosta, C. M., Poliotto, S., Abrego, D., Bradley, D., de Esteban, S., Mir, F., ... & Tusman, G. (2023). Effect of an individualized lung protective ventilation on lung strain and stress in children undergoing laparoscopy: an observational cohort study. Anesthesiology, 10-1097.

Li, Y., Xu, H. L., Kang, X. W., Xu, S., & Mou, Z. F. (2023). MiR-2113 overexpression attenuates sepsis-induced acute pulmonary dysfunction, inflammation and fibrosis by inhibition of HMGB1. Heliyon.

De Meyer, G. R., Morrison, S. G., & Schepens, T. (2023). Validity of volumetric capnography for the quantification of dead space during flow-controlled ventilation with active expiratory flow. European Journal of Anaesthesiology| EJA, 10-1097.

Mälberg, J., Marchesi, S., Spangler, D., Hadziosmanovic, N., Smekal, D., & Rubertsson, S. (2023). Continuous chest compressions are associated with higher peak inspiratory pressures when compared to 30: 2 in an experimental cardiac arrest model. Intensive care medicine experimental, 11(1), 75.

Mattei, R. B. (2023). Cálculo de la presión transpulmonar a través del monitoreo con balón esofágico durante la fase de soporte total de la ventilación mecánica invasiva. Argentinian Journal of Respiratory & Physical Therapy, 5(3).

Benites, M. H., Torres, D., Poblete, F., Labbe, F., Bachmann, M. C., Regueira, T. E., ... & Retamal, J. (2023). Effects of changes in trunk inclination on ventilatory efficiency in ARDS patients: quasi-experimental study. Intensive care medicine experimental, 11(1), 65.

Pistillo, N., Castelluccio, P., Suzuki, I., & Castiblanco, L. (2023). Mechanical Power Correlates With Stress, Strain, and Atelectrauma Only When Normalized to Aerated Lung Size in Patients With Acute Respiratory Distress Syndrome. Critical Care Explorations, 5(10), e0982.

Núñez Silveira, J. M., Borrajo, L., Ruiz, V. R., Ceballos, I., Ems, J., & Gallardo, A. (2023). Monitorización avanzada durante la desvinculación de la ventilación mecánica invasiva en el trasplante unipulmonar. Medicina (Buenos Aires), 83(4), 617-621.

Riva, D. A., Evangelista, C. A., & Puleston, P. F. (2023). Estimación online de modelos no lineales del sistema pulmonar bajo respiración asistida. In VII Jornadas de Investigación, Transferencia y Extensión de la Facultad de Ingeniería (La Plata, 25 al 27 de abril de 2023).

Pérez, J., Dorado, J. H., Accoce, M., & Plotnikow, G. A. (2023). Airway and transpulmonary driving pressure by end-inspiratory holds during pressure support ventilation. Respiratory Care, 68(11), 1483-1492.

Capdevila, M., De Jong, A., Aarab, Y., Vonarb, A., Carr, J., Molinari, N., ... & Jaber, S. (2023). Protocol: Which spontaneous breathing trial to predict effort to breathe after extubation according to five critical illnesses: the cross-over GLOBAL WEAN study protocol. BMJ Open, 13(7).

Réginault¹, T., Alejos, R. M., Burle, J. F., Coueron, R., Frison, E., & Vargas¹, F. (2023). Comparison of the impact of three inspiratory muscle training programs on diaphragm strength and endurance in intubated and mechanically ventilated patients with difficult weaning: a multicentric randomized controlled trial.

Campos, M. D., Palazzi, L. H., Böhm, S. H., & Tusman, G. (2023). Effects of apparatus dead space on volumetric capnograms in neonates with healthy lungs: a simulation study. Pediatric Anesthesia, 33(11), 973-982.

Mari, A., Cartailler, J., Barbarot, N., Legay, F., Tinelli, A., Joachim, J., & Vallée, F. (2023). A New Dynamic Slow-Flow Esophageal Balloon Pressure-Volume Curve Calibration Method to Assess Transpulmonary Pressure Monitoring. Respiratory Care.

Thille, A. W., Marie, D., Reynaud, F., Barrau, S., Beuvon, C., Bironneau, V., ... & Drouot, X. (2023). Sleep Assessment in Critically Ill Subjects With Acute Hypoxemic Respiratory Failure. Respiratory Care.

Gonzalez, I., Dominguez, C. B., Di Salvo, E., Loustau, M. P., Acevedo, V. S., Celano, M. D., ... & Plotnikow, G. A. (2023). Behavior of the Endotracheal Tube Cuff Pressure During a Routine Control Maneuver With Different Manometers-Bench Study. Respiratory Care.

Vieira, F., Rodrigues, A., Schreiber, A., Brault, C., Subira, C., & Brochard, L. (2023). Comparing Physiological Effects of Asymmetrical vs. Standard High-Flow Nasal Cannula: A Bench Study. In Critical Care Canada Forum 2022 (Vol. 69).

Schranc, Á., Diaper, J., Südy, R., Peták, F., Habre, W., & Albu, G. (2023). Lung recruitment by continuous negative extra-thoracic pressure support following one-lung ventilation: an experimental study. Frontiers in Physiology, 14, 806.

Rohrs, E., Parfait, M., Joussellin, V., Reynolds, S., Similowski, T., Demoule, A., & Dres, M. (2023). Diaphragm Neurostimulation-Assisted Ventilation in ARDS: A Proof-Of-Concept Human Study. In C104. CLINICAL AND TRANSLATIONAL STUDIES IN ALI AND ARDS (pp. A6068-A6068). American Thoracic Society.

De Meyer, G. R., Flamey, L., Adriaensens, I., Van der Aerschot, M., Van de Walle, H., Vanmarsenille, I., ... & Schepens, T. (2023). The Relationship Between Esophageal Pressure and Diaphragm Thickening Fraction in Spontaneously Breathing Sedated Children: A Feasibility Study. Pediatric Critical Care Medicine, 10-1097.

Bassi, T. G., Rohrs, E. C., Fernandez, K. C., Ornowska, M., Nicholas, M., Wittmann, J., ... & Reynolds, S. C. (2023). Phrenic nerve stimulation mitigates hippocampal and brainstem inflammation in an ARDS model. Frontiers in Physiology, 14, 1182505.

Rohrs, E. C., Bassi, T. G., Nicholas, M., Wittmann, J., Ornowska, M., Fernandez, K. C., ... & Reynolds, S. C. (2023). Risk factors for ventilator-induced-lung injury develop three to five times faster after a single episode of lung injury. Canadian Journal of Respiratory Therapy: CJRT= Revue Canadienne de la Thérapie Respiratoire: RCTR, 59, 103.

Beqiri, E., Smielewski, P., Guérin, C., Czosnyka, M., Robba, C., Bjertnæs, L., & Frisvold, S. K. (2023). Neurological and respiratory effects of lung protective ventilation in acute brain injury patients without lung injury: brain vent, a single centre randomized interventional study. Critical Care, 27(1), 115.

Dorado, J. H., Pérez, J., Accoce, M., Navarro, E., Gilgado, D. I., Cardoso, G. P., ... & Brochard, L. J. (2023). Oxygenation or Driving Pressure for Setting PEEP in Obese Patients With COVID-19 ARDS. Respiratory Care, 68(2), 260-264.

De Meyer, G. R., Morrison, S. G., Saldien, V., Jorens, P. G., & Schepens, T. (2023). Minimizing Lung Injury During Laparoscopy in Head-Down Tilt: A Physiological Cohort Study. Anesthesia & Analgesia, 137(4), 841-849.

De Meyer, G. R. A., Morrison, S. G., Saldien, V., Jorens, P. G., & Schepens, T. (2022). Reproducible determination of transpulmonary pressures. MethodsX, 9, 101696.

Arellano, D. H., Tobar, E. A., Lazo, M. T., Rojas, V. A., Gajardo, A. I., Montecinos, N., ... & Cornejo, R. A. (2022). Assessment of a splitter for protective dual-patient ventilation in patients with acute respiratory distress syndrome. British Journal of Anaesthesia, 128(5), e314-e317.

Damiani, F., Basoalto, R., Bachmann, M. C., Jalil, Y., Acuña, V., Diaz, G., ... & Bruhn, A. (2022). Impact of Awake Prone Positioning on Inspiratory Effort and Work of Breathing. A Physiological Study in Healthy Subjects. In A42. ARF/ARDS (pp. A1500-A1500). American Thoracic Society.

Dos Santos Rocha, A., Diaper, J., Balogh, A. L., Marti, C., Grosgurin, O., Habre, W., ... & Südy, R. (2022). Effect of body position on the redistribution of regional lung aeration during invasive and non-invasive ventilation of COVID-19 patients. Scientific Reports, 12(1), 11085.